Targeted Genome Editing Using Site-Specific Nucleases - ZFNs, TALENs, and the CRISPR/Cas9 System

de Springer Tokyo
État : Neuf
160,29 €
TVA incluse - Livraison GRATUITE
Springer Tokyo Targeted Genome Editing Using Site-Specific Nucleases - ZFNs, TALENs, and the CRISPR/Cas9 System
Springer Tokyo - Targeted Genome Editing Using Site-Specific Nucleases - ZFNs, TALENs, and the CRISPR/Cas9 System

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160,29 € dont de TVA
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Livraison : entre mardi 5 octobre 2021 et jeudi 7 octobre 2021
Vente et expédition: Dodax EU

La description

This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.

Détails du produit

Commentaire illustrations:
11 schwarz-weiße und 34 farbige Abbildungen, 12 schwarz-weiße Tabellen, Bibliographie
Éditeur:
Yamamoto, Takashi
Remarks:

Equips readers with a basic understanding of genome editing methods, allowing for further developments in the field


Provides detailed methods for generation of engineered nucleases


Describes applications of genome editing methods in various organisms and in stem cells

Type de média:
Couverture rigide
Éditeur:
Springer Tokyo
Langues:
Anglais
Nombre de pages:
205

Données de base

Type d'produit:
Livre relié
Date de publication:
20 janvier 2015
Dimensions du colis:
0.234 x 0.152 x 0.018 m; 0.476 kg
GTIN:
09784431552260
DUIN:
SA0ASK7HFN6
160,29 €
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